Tricyclic compounds having activity specific for integrins,...

C - Chemistry – Metallurgy – 07 – C

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C07C 281/12 (2006.01) A61K 31/19 (2006.01) A61K 31/33 (2006.01) A61K 31/415 (2006.01) A61K 31/505 (2006.01) A61K 31/55 (2006.01) C07C 45/51 (2006.01) C07C 45/63 (2006.01) C07C 45/67 (2006.01) C07C 45/71 (2006.01) C07C 49/747 (2006.01) C07C 49/755 (2006.01) C07C 281/18 (2006.01) C07C 337/08 (2006.01) C07D 233/52 (2006.01) C07D 235/30 (2006.01) C07D 239/18 (2006.01) C07D 243/04 (2006.01) C07D 317/70 (2006.01) C07D 401/02 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2249471

Compounds of formula (I), wherein R¿1?, R¿2?, R¿3?, R¿4?, R¿5? and G are as defined in the description and the dotted lines indicate an optional second bond, as well as the acid, base and ester addition salts thereof, a method for preparing said compounds, intermediates therefor, the use of said compounds as drugs, and pharmaceutical compositions containing same, are disclosed.

L'invention a pour objet les produits de formule (I) dans laquelle R1, R2, R3, R4, R5 et G sont tels que définis dans la description, les traits en pointillés représentent une éventuelle seconde liaison, ainsi que les sels d'addition avec les acides et les bases et les esters, leur procédé de préparation et les intermédiaires de ce procédé, leur application à titre de médicaments et les compositions pharmaceutiques les renfermant.

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