Tricyclic compounds useful as hiv reverse transcriptase...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) A61K 45/06 (2006.01) A61P 31/18 (2006.01) C07D 221/00 (2006.01) C07D 239/00 (2006.01) C07D 471/14 (2006.01)

Patent

CA 2387896

The present invention relates to tricyclic compounds of formula (I) or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

La présente invention concerne des composés tricycliques représentés par la formule générale (I), des formes stéréoisomères, des mélanges stéréoisomères ou leurs formes de sels pharmaceutiquement acceptables, utiles en tant qu'inhibiteurs de la transcriptase inverse du VIH. La présente invention concerne également des compositions pharmaceutiques et des kits de diagnostic renfermant ces composés, et des procédés d'utilisation de ces composés pour traiter des infections virales ou comme solution étalon ou réactif pour le dosage.

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