Tricyclic compounds useful in treating iron disorders

Details Tricyclic compounds useful in treating iron disorders Tricyclic compounds useful in treating iron disorders

C - Chemistry, Metallurgy

07

D

C07D 307/91 (2006.01) A61K 31/155 (2006.01) A61K 31/343 (2006.01) A61K 31/381 (2006.01) A61P 3/02 (2006.01) A61P 39/04 (2006.01) C07C 335/32 (2006.01) C07D 311/86 (2006.01) C07D 327/08 (2006.01) C07D 333/76 (2006.01) C07D 337/10 (2006.01)

Patent

CA 2678895

This invention is directed to, for example, compounds of formula (I): wherein n, m, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, for the treatment of iron disorders. This invention is also directed to pharmaceutical compositions comprising the compounds and methods of using the compounds to treat iron disorders.

L'invention concerne, par exemple, des composés de formule (I) : où n, m, R1, R2, R3, R4, R5, R6, R7 et R8 sont tels que définis ici, sous la forme d'un stéréoisomère, d'un énantiomère, d'un tautomère de ceux-ci ou de mélanges de ceux-ci ; ou un sel, un solvate ou un promédicament de ceux-ci, pour le traitement de troubles dus au fer. L'invention concerne également des compositions pharmaceutiques comprenant les composés et des procédés d'utilisation des composés pour traiter les troubles dus au fer.

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