Tricyclic derivatives of 5,6-dihydro-11h-dibenzo (b, e)...

Details Tricyclic derivatives of 5,6-dihydro-11h-dibenzo (b, e)... Tricyclic derivatives of 5,6-dihydro-11h-dibenzo (b, e)...

C - Chemistry, Metallurgy

07

D

260/241.25

C07D 223/20 (2006.01)

Patent

CA 1226282

ABSTRACT TRICYCLIC DERIVATES OF 5,6-DIHYDRO-llH-DIBENZO (B,E) AZEPIN- 6-ONE HAVING PHARMACOLOGICAL ACTIVITY, AND RELATIVE PRODUCTION METHODS A pharmacologically active compound has the general formula Image in which R is a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms; R1 and R2, which can be different, represent a hydrogen atom, a hydroxyl group, an alkyl group, an alkoxy group, an arylalkyl group, or an arylalkoxy group, or can jointly represent an oxygen atom or a CHCOORl' group where R1 is a hydrogen atom or an alkyl group; and R3 represents a hydrogen or halogen atom or an alkyl, NH2, NO2, NHCO-alkyl, NHCO-aryl, NHCONH-alkyl or NHCONH-aryl group. These compounds act on the central nervous system and have an anti-convulsant sedative activity.

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