C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/211, 260/264
C07D 491/044 (2006.01) A61K 31/50 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01)
Patent
CA 1314885
IN THE UNITED STATES PATENT & TRADEMARK OFFICE PATENT APPLICATION entitled: Novel tricyclic derivatives which are agonists of cholinergic receptors, and drugs in which they are present in the names of: Camille Georges WERMUTH Paul WORMS Jean-Jacques BOURGUIGNON Roger BRODIN Assignee: SANOFI ABSTRACT OF THE DISCLOSURE The invention relates to novel tricyclic derivatives which are agonists of cholinergic receptors. These derivatives have the formula Image (I) in which X = O, S, -OCH2- or -SCH2-; R1 = H or halogen; and R2 = Image , in which Alk is an alkylene group and R3 and R4, which are identical or different, are hydrogen or a lower alkyl group, or R3 and R4, with the nitrogen atom to which they are bonded, form a 5- or 6-membered cyclic amino group optionally containing a second heteroatom; or R2 is a group Image where R5 = C1-C4-alkyl. Application: agonists of cholinergic receptors.
586850
Bourguignon Jean-Jacques
Brodin Roger
Wermuth Camille G.
Worms Paul
Bourguignon Jean-Jacques
Brodin Roger
Sim & Mcburney
Societe Anonyme: Sanofi
Wermuth Camille G.
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