C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/052 (2006.01) A61K 31/40 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2698436
The present invention relates to a tricyclic heterocyclic derivative of Formula (I) wherein the variables are as defined in the specification. The present invention further relates to pharmaceutical compositions comprising these compounds and to their use in therapy, in particular for the treatment of serotonin-mediated disorders such as obesity, schizophrenia and cognitive dysfunction.
La présente invention a trait à un dérivé hétérocyclique tricyclique de formule (I), dans laquelle les variables sont telles que définies dans le mémoire descriptif. La présente invention a trait, en outre, à des compositions pharmaceutiques contenant lesdits composés et à leur utilisation dans le cadre thérapeutique, en particulier pour le traitement d'affections à médiation par la sérotonine, comme l'obésité, la schizophrénie et le dysfonctionnement cognitif.
Grove Simon James Anthony
Kiyoi Takao
Mistry Ashvinkumar Dhirubhai
Ray Peter Christopher
Wishart Grant
Fetherstonhaugh & Co.
N.v. Organon
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