Tricyclic indole-2-carboxylic acid compound used as nmda...

C - Chemistry – Metallurgy – 07 – D

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C07D 209/90 (2006.01) A61K 31/40 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2362700

The present invention provides a compound which is a tricyclic indole-2- carboxylic acid of formula (1) or a prodrug thereof or a pharmaceutically acceptable salt of the said acid or prodrug, or a solvate of the said acid, prodrug or salt, which is a potent N-methyl-D-aspartate receptor antagonist.

La présente invention concerne un composé qui est un acide indole-2-carboxylique tricyclique représenté par la formule générale (1) ou l'un de ses promédicaments ou l'un des sels pharmaceutiquement admis de l'acide considéré ou du promédicament, ou un solvat de l'acide considété, du promédicament considéré ou du sel considéré, qui est un puissant antagoniste du récepteur N-méthyl-D-aspartate.

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