Tricyclic inhibitors of poly(adp-ribose) polymerases

C - Chemistry – Metallurgy – 07 – D

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C07D 487/06 (2006.01) A61K 31/5517 (2006.01)

Patent

CA 2382404

Compounds of the formula (I) are poly(ADP-ribosyl)transferase in-hibitors. Such compounds are useful as therapeutics in treating cancers and in amelio-rating the effects of stroke, head trauma, and neurodegenerative disease.

Les composés selon l'invention, représentés par la formule (I), sont des inhibiteurs de la poly(ADP-ribosyl)transférase. Lesdits composés sont utilisés en thérapie pour traiter les cancers et pour atténuer les effets de l'accident vasculaire cérébral, du traumatisme crânien et des maladies neurodégénératives.

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