Tricyclic pteridinones and a process for their preparation

Details Tricyclic pteridinones and a process for their preparation Tricyclic pteridinones and a process for their preparation

C - Chemistry, Metallurgy

07

D

167/211, 260/242

C07D 487/14 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2029651

This invention relates to novel tricyclic pteridinones, their aza analogs and their pharmaceutically acceptable salts. Further encompassed by the invention is a novel process for the production of the tricyclic pteridinones and their aza analogs. The compounds of the invention exhibit cardiovascular properties, particularly mixed vasodilation and selective venous and arterial dilation. Pharmaceutical compositions are proposed for the compounds.

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