Tricyclic pyrazole derivatives

Details Tricyclic pyrazole derivatives Tricyclic pyrazole derivatives

C - Chemistry, Metallurgy

07

D

C07D 231/54 (2006.01) A61K 31/415 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/505 (2006.01) A61K 31/53 (2006.01) A61P 29/00 (2006.01) C07D 231/00 (2006.01) C07D 307/00 (2006.01) C07D 333/00 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/04 (2006.01) C07D 417/12 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2350235

This invention relates to certain 3-aryl or 3-heteroaryl pyrazoles with 4,5(3,4)-bicyclic ring fusion which are inhibitors of protein kinase activity, of which some are novel compounds, to pharmaceutical compositions containing these pyrazoles and to processes for preparing these pyrazoles.

L'invention concerne certains 3-aryle 3-hétéroaryle pyrazoles avec un noyau de fusion 4,5(3,4)-bicyclique qui sont des inhibiteurs de l'activité de protéine kinase et dont certains sont des composés nouveaux; l'invention concerne aussi des compositions pharmaceutiques à base de ces pyrazoles et des procédés de fabrication correspondants.

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