Tricyclic pyrazole derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 495/04 (2006.01) A61K 31/416 (2006.01) A61K 31/4162 (2006.01) A61P 35/00 (2006.01) C07D 231/54 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 451/04 (2006.01)

Patent

CA 2409225

This invention relates to compounds of formula I which are inhibitors of protein kinase activity, of which some are novel compounds, to pharmaceutical compositions containing these pyrazoles and to processes for preparing these pyrazoles.

L'invention concerne certains 3-aryle 3-hétéroaryle pyrazoles avec un noyau de fusion 4,5(3,4)-bicyclique qui sont des inhibiteurs de l'activité de protéine kinase et dont certains sont des composés nouveaux. L'invention concerne également des compositions pharmaceutiques à base de ces pyrazoles et des procédés de fabrication correspondants.

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