Tricyclic pyrazole derivatives, process for their...

Details Tricyclic pyrazole derivatives, process for their... Tricyclic pyrazole derivatives, process for their...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/415 (2006.01) A61K 31/4162 (2006.01) A61P 25/28 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 413/04 (2006.01) C07D 471/04 (2006.01) C07D 471/14 (2006.01) C07D 471/22 (2006.01) C07D 487/14 (2006.01) C07D 495/04 (2006.01) C07D 498/14 (2006.01)

Patent

CA 2476822

Compounds which are tricyclic pyrazole derivatives and analogues thereof, as set forth in the specification, or pharmaceutically acceptable salts thereof, together with pharmaceutical compositions comprising them are disclosed; these compounds or compositions are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders.

Composés qui sont des dérivés des de pyrazole tricyclique et leurs analogues, indiqués dans la spécification, ou leurs sels pharmaceutiquement acceptables ainsi que compositions pharmaceutiques les comprenant; ces composés ou compositions sont utiles dans le traitement de maladies provoquées par ou associées avec une activité altérée de protéine kinase, telles que le cancer, les troubles prolifératifs de cellules, la maladie d'Alzheimer, les infections virales, les maladies auto-immunes et les troubles neuro-dégénératifs.

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