Tricyclic pyridine n-oxides vasopressin agonists

Details Tricyclic pyridine n-oxides vasopressin agonists Tricyclic pyridine n-oxides vasopressin agonists

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/551 (2006.01) A61P 7/12 (2006.01) A61P 13/00 (2006.01) C07D 221/00 (2006.01) C07D 243/00 (2006.01)

Patent

CA 2358894

The present invention provides compounds of general formula (I) as well as methods and pharmaceutical compositions utilizing these compounds for the inducement of temporary delay of urination or the treatment of disorders which may be remedied or alleviated by vasopressin agonist activity, including diabetes, insipidus, nocturnal enuresis, nocturia, urinary incontinence, bleeding and coagulation disorders.

Cette invention a trait à des composés correspondant à la formule générale (I) ainsi qu'à des méthodes et à des compositions pharmaceutiques utilisant ces composés pour déclencher un retard temporaire de la miction ou pour traiter des troubles pouvant être soignés ou atténués par une activité d'agoniste de la vasopressine, notamment le diabète insipide, l'énurésie nocturne, la polyurie nocturne, l'incontinence urinaire, l'effusion sanguine et des troubles de la coagulation.

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