C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/239.5
C07D 487/04 (2006.01) C07D 207/16 (2006.01)
Patent
CA 1171083
Abstract A process for the preparation of new tricyclic pyrroles of the general formula I (I) Image wherein R1 denotes a hydrogen atom or an alkyl radical with 1 to 4 carbon atoms, R2 denotes a hydrogen atom, an alkyl radical with 1 to 4 carbon atoms or an alkenyl radical with 3 to 5 carbon atoms and R3 denotes an alkyl radical which has 1 to 4 carbon atoms and is-optionally substituted by a dialkylamino group with 1 to 4 carbon atoms in each alkyl radical, or denotes an alkenyl radical with 3 to 5 carbon atoms, or R2 and R3 together, with the inclusion of the nitrogen atom to which they are bonded, denote a pyrrolidino, piperidino, morpholino or perhydroazepino ring, a 1-piperazinyl radical which is optionally substituted in the 4-position by a methyl, ethyl or benzyl group, or a 1-homopiperazinyl radical which is optionally substituted in the 4-position by a methyl group, R4, R5 and R6 are identical or different and denote hydrogen or alkyl with 1 to 4 carbon atoms and n represents 1 or 2, and their acid addition salts is given. The compounds produced according to the invention have a pro- tective action on the stomach and intestines and are suitable for the treatment of illnesses based on diseases of the stomach or intestine.
395304
Byk Gulden Lomberg Chemische Fabrik G.m.b.h.
Fetherstonhaugh & Co.
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