C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/242.01
C07D 487/04 (2006.01)
Patent
CA 1208636
TRICYCLIC QUINAZOLINONES Abstract Compounds of formula I Image I wherein a) R1 represents one of the following groups Image wherein m represents 0, 1, 29 3 or 4, p represents 1 or 2, q represents 0, 1 or 2 R7 represents hydrogen or C1-2alkyl, R8 represents hydrogen, halogen or C1-3alkyl, R9 represents hydrogen, halogen, C1-4alkyl, trifluoromethyl or nitro, R2, R3 and R4 represent, independently, hydrogen or C1-2alkyl, R5 represents hydrogen, halogen, C1-4alkyl, trifluoromethyl or nitro and R6 represents hydrogen, halogen or C1-3alkyl, and n represents 0 or 1 whereby at least one of R2, R3 and R4 is hydrogen, or b) R1 represents C1-8alkyl, unsubstituted or substituted by 1 to 3 fluorine atoms R5 is in b-position and represents fluorine, chlorine or trifluoro- methyl, n represents 0 or 1 and R2, R3, R4 and R6 represent hydrogen, with the proviso that R1 is other than methyl when R5 is chlorine and n is 1, or c) R1 represents C3-6alkenyl, C3-6alkynyl, C3-8cycloalkyl, norbornyl or C3-7cycloalkyl-(C1-3)-alkyl, R2, R3 and R4 represent, independently, hydrogen or C1-2alkyl, R5 is in b-position and represents halogen, C1-4alkyl or trifluoro- methyl, R6 represents hydrogen, halogen or C1-3alkyl, n represents 0 or 1, in free base form or in the form of a pharmaceutically acceptable acid addition salt for use as traquillizers. These compounds are indicated for use as pharmaceuticals, in particular as tranquillizers.
411397
Hardtmann Goetz E.
Houlihan William J.
Kirby Eades Gale Baker
Sandoz Ltd.
LandOfFree
Tricyclic quinazolinones does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tricyclic quinazolinones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tricyclic quinazolinones will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1189188