Tricyclic spiro compound comprising acyl group bound to...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/20 (2006.01) A61K 31/499 (2006.01) A61K 31/506 (2006.01) A61K 31/527 (2006.01) A61P 7/02 (2006.01) C07D 498/20 (2006.01) C07D 513/20 (2006.01)

Patent

CA 2602025

It is intended to provide an anticoagulant that has an extremely excellent FXa inhibitory action and an extremely weak hERG channel inhibitory action and can be orally administered, which is a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof.

La présente invention a pour objet un anticoagulant présentant un effet inhibiteur de FXa particulièrement excellent et un effet inhibiteur du canal hERG particulièrement faible, ledit anticoagulant pouvant être administré par voie orale, ledit anticoagulant étant un composé de formule (I) suivante ou un sel de qualité pharmaceutique dudit composé.

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