Tricyclic spiro derivatives as crth2 modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/10 (2006.01) A61K 31/407 (2006.01) A61P 29/00 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2602965

The present invention is related to the use of spiro derivatives of Formula (I) for the treatment and/or prevention of allergic diseases, inflammatory dermatoses and other diseases with an inflammatory component. Specifically, the present invention is related to the use of spiro derivatives for the modulation of CRTH2 activity.

L'invention concerne l'utilisation de dérivés spiro de formule (I) pour traiter et/ou pour prévenir des maladies allergiques, des dermatoses inflammatoires et d'autres maladies présentant une composante inflammatoire. En particulier, l'invention concerne l'utilisation de dérivés spiro pour moduler l'activité de CRTH2.

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