Tricyclic steroid hormone nuclear receptor modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 405/06 (2006.01) A61K 31/4184 (2006.01) A61K 31/454 (2006.01) A61K 31/5377 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2549053

The present invention provides a compound of the formula (I): or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart disease, hypertension, rheumatoid arthritis or inflammation, comprising administering to a patient in thereof an effective amount of a compound of Formula (I).

L'invention porte sur un composé de formule (I) ou ses sels pharmacocompatibles; sur des préparations pharmaceutiques contenant une dose efficace dudit composé associée à un support, à un diluant ou à un excipient adéquates; et sur des méthodes de traitement de troubles physiologiques dont en particulier: l'insuffisance cardiaque congestive; l'hypertension; l'arthrite rhumatoïde et les inflammations consistant à administrer à un patient le nécessitant une dose efficace dudit composé.

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