Tricyclopolyazamacrocyclophosphonic acids, complexes and...

Details Tricyclopolyazamacrocyclophosphonic acids, complexes and... Tricyclopolyazamacrocyclophosphonic acids, complexes and...

C - Chemistry, Metallurgy

07

D

C07D 471/22 (2006.01) A61K 49/00 (2006.01) C07D 471/18 (2006.01) C07F 5/00 (2006.01) C07F 9/6561 (2006.01) C07F 13/00 (2006.01) C07F 15/02 (2006.01) C07K 2/00 (2006.01) C07K 16/18 (2006.01) G01R 33/28 (2006.01)

Patent

CA 2162172

Tri- and tetra-cyclopolyazamacrocyclophosphonic acid compounds and their derivatives are disclosed which may form inert complexes with Gd, Mn or Fe ions. The overall charge of the complex can be varied to alter the in vivo biolocalization. The complexes are useful as contrast agents for diagnostic purposes.

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