Trihemihydrate, anhydrate and hydrate forms of cefdinir

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 501/22 (2006.01) A61K 31/546 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2558629

The present invention relates to trihemihydrate, novel lower hydrate and anhydrate forms of 7-[2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamide]-3-vinyl- 3-cephem-4-carboxylic acid (syn isomer), methods for their preparation, and pharmaceutical compositions comprising these forms.

La présente invention concerne le trihémihydrate, de nouvelles formes d'anhydrate et d'hydrate inférieur de 7-[2-(2-aminothiazol-4-yl)-2-hydroxyiminoacétamide]-3-vinyl-3-cephem-4-acide carboxylique (syn-isomère), leurs méthodes de préparation, et des compositions pharmaceutiques contenant ces formes.

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