C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 493/20 (2006.01) A61K 31/357 (2006.01) A61P 33/06 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2469223
This application relates to compounds of the general formula (11), and pharmaceutically acceptable salts thereof, in which R is selected from the group comprising optionally substituted alkyl, aryl, bisalkyl or bisaryl ester, bisalkyl or bisaryl ether, acetal, ketal, boronate, silyl ether, carbamate, carbonate, sulphate, sulphonate, phosphate and phosphonate, and to processes for their production. The compounds are useful as medicaments, in particular for the treatment of malaria and cancer.
La présente invention concerne des composés représentés par la formule (I) et des sels pharmaceutiquement acceptables de ces derniers, dans lesquels R est sélectionné dans le groupe comprenant alkyle, aryle, ester de bisaryle ou de bisalkyle, éther de bisalkyle ou de bisaryle, acétal, cétal, boronate, éther de silyle, carbamate, carbonate, sulfate, sulfonate, phosphate et phosphonate facultativement substitué, et des procédés de production de ces derniers. Ces composés sont utiles en tant que médicaments, notamment pour le traitement du paludisme et du cancer. Formule (I)
Higson Adrian Peter
Irving Edward
O'neill Paul Michael
Taylor Sara
Moffat & Co.
Ufc Limited
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