C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/5.04, 167/10
C07K 5/02 (2006.01) C07K 5/097 (2006.01)
Patent
CA 1275550
ABSTRACT OF THE DISCLOSURE The invention relates to the peptides of the formula: Image ( I ) in which: - R represents hydrogen or a protecting group for the terminal amine group, such as t-butoxycarbonyl (Boc), benzyloxycarbonyl (Z) or lower alkanoyl; - X1 represents either beta-Ala or a direct bond between R and the terminal amine group of the amino acid TRP; - TRP denotes either the L isomer or the D isomer of tryptophan; - X2 represents L-leucine, L-methionine or L- norleucine; and - Y denotes hydrogen, a halogen atom (preferably fluorine or chlorine), a trifluoromethyl group, a cyano group or a nitro group. These peptides inhibit gastric secretion.
497718
Bali Jean-Pierre
Castro Bertrand
Demarne Henri
Magous Richard
Martinez Jean
Bali Jean-Pierre
Castro Bertrand
Demarne Henri
Etablissement Public:centre National de La Recherche Scientifiqu
Magous Richard
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