C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/097 (2006.01) A61K 38/06 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2131982
This invention provides (1R, 4aR, 8aR)- 1,2,3,4,5,6,7,8-perhydroisoquinolin-1-carbonyl-(L)-prolinyl-(L)- arginine aldehyde and pharmaceutically acceptable salts and solvates thereof, pharmaceutical formulations containing said compounds and methods of their use as thrombin inhibitors, coagulation inhibitors and thromboembolic disorder agents.
Gesellchen Paul D.
Shuman Robert T.
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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