Tripeptidyl peptidase inhibitors

Details Tripeptidyl peptidase inhibitors Tripeptidyl peptidase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 209/42 (2006.01) A61K 31/40 (2006.01) C07D 209/60 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2315703

The invention is relative to a compound of formula (I), wherein R1, R2, R3 and n are as defined, together with a process for its preparation. The invention is also relative to the use of a compound (I) as an inhibitor of the CCK-inactivating peptidase tripeptidyl peptidase (TPP II). The invention concerns in particular the treatment of eating disorder, obesity, psychotic syndromes and associated psychiatric disorders. It concerns also the cosmetic use of a compound (I) in particular to aid slimming.

L'invention porte sur un composé de formule (I), dans laquelle R<1>, R<2>, R<3> et n sont comme définis, et sur leur procédé de préparation. L'invention concerne aussi l'utilisation d'un composé (I) en tant qu'inhibiteur de la CCK, la tripeptidyl peptidase (TPP II). Elle se rapporte notamment au traitement de troubles alimentaires, de l'obésité, de syndromes psychotiques et de troubles psychiatriques associés ainsi qu'à l'utilisation dans la cosmétique d'un composé (I), notamment pour favoriser l'amaigrissement.

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