Triphenylalkene derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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260/602.3, 260/3

C07D 295/08 (2006.01) C07C 45/46 (2006.01) C07C 45/67 (2006.01) C07C 45/68 (2006.01) C07C 45/71 (2006.01) C07C 49/83 (2006.01) C07C 49/84 (2006.01) C07C 51/60 (2006.01) C07D 295/092 (2006.01) C07D 309/12 (2006.01) C07D 339/08 (2006.01)

Patent

CA 1088950

ABSTRACT The disclosure relates to 1- p-amino- alkoxy pehnyl-1-p-hyroxyphenyl-2-phenylalk-1-ene derivatives, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess anti-oestrogenic activity and are useful in the treatment of a?ovulatory infertility and of breast tumours. Representative of the compounds disclosed is 1-(p-.beta.-dimethylaminoethoxy- phenyl)-trans-1-hydroxyphenyl-2-p-tolylbut-1-ene.

309715

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