C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2499996
A recombinant plasmid or expression vector comprising a sequence encoding a trans-acting hairpin ribozyme or inserted RNA flanked by 5' and 3' self- cleavage cis-acting hairpin ribozymes, which produces a long RNA transcript that undergoes self-catalyzed cleavage at the 5' and 3' sides of the trans- acting ribozyme or inserted RNA.
L'invention concerne un vecteur d'expression ou de plasmide recombiné comprenant une séquence codant pour un ribozyme en épingle à cheveux agissant en trans ou ARN inséré flanqué de ribozymes en épingle à cheveux agissant en cis à autoclivage 5' et 3', lequel vecteur produit un long transcrit d'ARN subissant un clivage auto-catalysé au niveau des côtés 5' et 3' du ribozyme agissant en trans ou ARN inséré.
Alvarez-Salas Luis
Dipaolo Joseph A.
Centro de Investigacion Y. de Estudios Avanzados Del I.p.n.
Department Of Health And Human Services The Government Of The United States Of America As Represented By
Smart & Biggar
LandOfFree
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