Triptolide lactone ring derivatives as immunomodulators and...

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 71/00 (2006.01) A61K 31/58 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2557260

Disclosed are compounds based on lactone ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.

La présente invention a trait à des composés à base de noyau de modifications lactone de triptolide et de triptolide hydroxylé, destinés à être utilisés en thérapie, telle que la thérapie contre la prolifération, anticancéreuse, et immunosuppressive.

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