C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/24 (2006.01) A61K 31/44 (2006.01) A61P 3/04 (2006.01)
Patent
CA 2732682
The present invention is directed to tripyridyl carboxamide compounds which are antago-nists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are in-volved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved. (Formula).
L'invention concerne des composés de tripyridyle carboxamide, qui sont des antagonistes de récepteurs d'orexine, et qui sont utiles pour le traitement ou la prévention de troubles neurologiques et psychiatriques, et de maladies dans lesquelles des récepteurs d'orexine sont impliqués. L'invention concerne également des compositions pharmaceutiques comprenant ces composés, et l'utilisation de ces composés et compositions dans la prévention ou le traitement de telles maladies dans lesquelles des récepteurs d'orexine sont impliqués (formule).
Coleman Paul J.
Mercer Swati P.
Reger Thomas S.
Roecker Anthony J.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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