Trisazolo¬2,3-c|¬1,3| benzodiazepines

Details Trisazolo¬2,3-c|¬1,3| benzodiazepines Trisazolo¬2,3-c|¬1,3| benzodiazepines

C - Chemistry, Metallurgy

07

D

260/239.3

C07D 487/04 (2006.01) C07D 249/08 (2006.01) C07D 249/10 (2006.01) C07D 249/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1215044

Trisazolo[2,3-c][1,3]benzodiazepines Abstract of the Disclosure The invention concerns 5-diazacycloalkyl-1,2,4-triazolo[2,3-c]- [1,3]benzodiazepines of formula I (I) Image wherein R1 is hydrogen, lower alkylthio, amino, (acyl, mono- or di-lower alkyl)-amino, lower alkoxy, acyloxy, lower alkyl, lower alkanoyl, hydroxy, halogen, trifluoromethyl, cyano, carboxy, lower alkoxycarbonyl, carbamoyl, mono- or di-lower alkyl-carbamoyl, hydroxy-lower alkyl or di-lower alkylamino-lower alkyl; CnH2n is lower alkylene separating both nitrogen atoms by 2 or 3 carbon atoms; R2 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, lower alkanoyl, aryl-lower alkyl, lower alkoxycarbonyl, phenyl lower alkoxycarbonyl or (hydroxy, lower alkanoyloxy, aryloxy or lower alkoxy)-lower alkyl having at least two carbon atoms; R3 and R4 independently represent hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen, trifluoromethyl, hydroxy, lower alkanoyloxy, sulfamoyl, mono- or di-lower alkylsulfamoyl; and R5 and R6 represent hydrogen or lower alkyl; the N-oxides; and salts.

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