Trisubstituted pyrimido[5,4-d]pyrimidines for modulating...

Details Trisubstituted pyrimido[5,4-d]pyrimidines for modulating... Trisubstituted pyrimido[5,4-d]pyrimidines for modulating...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2129179

Abstract Pyrimido Pyrimidine Compounds The invention relates to compounds of formula I Image (I) (wherein Ra, Rb and Rc are as defined in claim 1) and the salts thereof, more particularly for pharmaceutical use the physiologically acceptable salts thereof, which have, inter alia, valuable pharmacological properties, particularly a sensitising effect on resistant tumours in chemotherapy, their use and processes for their preparation.

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