C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 63/00 (2006.01) A61K 31/216 (2006.01) A61K 31/56 (2006.01) A61P 31/04 (2006.01) A61P 31/10 (2006.01) A61P 33/14 (2006.01) A61P 35/00 (2006.01) C07C 69/757 (2006.01) C07J 53/00 (2006.01)
Patent
CA 2635318
The invention relates to triterpenequinone and triterpenephenol derivatives, their pharmaceutically acceptable 5 salts, prodrugs, solvates or stereoisomers as selective blocking agents of the choline kinase enzyme, pharmaceutical compositions containing them and their use in the treatment of tumors and parasitic diseases or diseases caused by viruses, bacteria or fungi.
La présente invention concerne des dérivés de triterpènequinone et de triterpènephénol, leurs sels promédicaments, solvates ou stéréo-isomères pharmaceutiquement acceptables, en tant qu'agents bloquants sélectifs de l'enzyme choline kinase, des compositions pharmaceutiques les contenant et leur utilisation pour le traitement de tumeurs et de maladies parasitaires ou de maladies causées par des virus, des bactéries ou des champignons.
Banez Coronel Monica
Estevez Braun Ana
Gutierrez Ravelo Angel
Lacal Sanjuan Juan Carlos
Perez Sacau Elisa
Consejo Superior de Investigaciones Cientificas
Smart & Biggar
Universidad de La Laguna
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