Triterpenes derivatives and uses thereof as antitumor agents...

Details Triterpenes derivatives and uses thereof as antitumor agents... Triterpenes derivatives and uses thereof as antitumor agents...

C - Chemistry, Metallurgy

07

J

C07J 63/00 (2006.01) A61K 31/704 (2006.01) A61P 35/00 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2586614

A compound of formula (I): Image wherein R1 is selected from the group consisting of H, .alpha.-L-Rhamnopyranose, .alpha.-D- Mannopyranose, .beta.-D-Xylopyranose, .beta.-D-Glucopyranose, and .alpha.-D- Arabinopyranose; R2 is selected from CH3, COOH, CH2OH, COOCH3 and CH2O-.alpha.-D-Arabinopyranose; with the proviso that the compound of formula (I) is not a compound of formula (I) wherein R1 is .beta.-D-Glucopyranose and R2 is COOH; wherein R1 is .alpha.-L-Rhamnopyranose and R2 is CH3; wherein R1 is .beta.-D-Glucopyranose and R2 is CH2OH; wherein R1 is .beta.-D-Xylopyranose and R2 is CH2OH; wherein R1 is .alpha.-L-Rhamnopyranose and R2 is COOCH3, wherein R1 is H and R2 is CH3; wherein R1 is H and R2 is CH2OH; wherein R1 is H and R2 is COOH; or wherein R1 is H and R2 is COOCH3, or a pharmaceutically acceptable salt thereof.

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