Tritium labelled n-mustard type compounds and a process for...

C - Chemistry – Metallurgy – 07 – B

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C07B 59/00 (2006.01) A61K 51/04 (2006.01) C07D 203/10 (2006.01)

Patent

CA 1271755

NOVEL TRITIUM LABELLED N-MUSTARD TYPE COMPOUNDS AND A PROCESS FOR THEIR PRODUCTION ABSTRACT The present invention describes novel tritium labelled nitrogen mustard type compounds, and their aziridinium type analog, and a process for the production of same. The compounds are of value in medical research and development and also as active ingredients of pharmaceutical compositions. The compounds can be used to develop analogs of human disease states and can also be used to evaluate the mechanism of neurotransmitter regulation and function, both in vitro and in vivo.

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