Trk tyrosine kinase receptor is the physiological receptor...

Details Trk tyrosine kinase receptor is the physiological receptor... Trk tyrosine kinase receptor is the physiological receptor...

G - Physics

01

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G01N 33/566 (2006.01) C07K 14/48 (2006.01) C07K 14/71 (2006.01) G01N 33/564 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2106080

The present invention relates to a complex comprising nerve growth factor (NGF) and trk-proto-oncogene protein. The present invention also relates to methods for detecting the presence of NGF and trk-proto-oncogene receptor. The present invention further relates to methods that may be used in diagnostics and therapeutics for neurodegenerative diseases such as Alzeimer's and Huntington's by detecting NGF-trk receptor pairs.

Complexe comprenant un facteur de croissance nerveuse (FCN) et une protéine trk-proto-oncogène. L'invention décrit également des méthodes permettant de détecter la présence du FCN et du récepteur trk-proto-oncogène, de même que des méthodes qui peuvent servir au diagnostic et au traitement des maladies neurodégénératives, comme la maladie d'Alzheimer ou la chorée de Huntington, en détectant les couples FCN-récepteur trk.

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