C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/0735 (2010.01) A61K 35/48 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2345397
Stable pluripotent trophoblast stem (TS) cell lines and uses of the cell lines are described. The cell lines comprise cells that (i) are capable of indefinite proliferation in vitro in an undifferentiated state; and (ii) are capable of differentiation into cells of the trophoblast lineage in vivo.
L'invention concerne des lignées cellulaires stables constituées de trophoblastes souches multipotents (TS) et l'utilisation desdites lignées cellulaires. Ces lignées cellulaires sont constituées de cellules capables i) de prolifération infinie in vitro à l'état indifférencié; et ii) de différenciation en cellules de la lignée trophoblastique in vivo.
Kunath Tilo
Rossant Janet
Tanaka Satoshi
Mount Sinai Hospital
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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