Truncated cystine-knot proteins

Details Truncated cystine-knot proteins Truncated cystine-knot proteins

C - Chemistry, Metallurgy

07

K

C07K 14/52 (2006.01) A61K 38/04 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2751445

The invention relates to the fields of protein chemistry, biology and medicine. More specifically, it relates to the design and preparation of proteinmimics of members of the cystine-knot growth factor superfamily. Further the invention relates to the use of these proteinmimics as a medicament or prophylactic agent. The invention provides proteinmimics of members of the cystine-knot growth factor superfamily, preferably for use in immunogenic and/or therapeutic compositions.

La présente invention concerne les domaines de la chimie des protéines, de la biologie et de la médecine. Elle concerne plus spécifiquement la conception et la préparation de protéines mimétiques de membres de la superfamille des facteurs de croissance à nud cystine. L'invention concerne en outre l'utilisation de ces protéines mimétiques en tant que médicament ou en tant qu'agent prophylactique. L'invention concerne des protéines mimétiques de membres de la superfamille des facteurs de croissance à nud cystine, de préférence destinées à être utilisées dans des compositions immunogènes et/ou thérapeutiques.

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