Truncated platelet-activating factor acetylhydrolase

Details Truncated platelet-activating factor acetylhydrolase Truncated platelet-activating factor acetylhydrolase

C - Chemistry, Metallurgy

12

N

C12N 9/14 (2006.01) C12N 9/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2267994

The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events.

Cette invention a trait à des séquences polynucléotidiques purifiées et isolées codant l'acétyl-hydrolase du facteur d'activation plaquettaire humain. Elle concerne également des substances et des méthodes visant à la production par recombinaison de produits d'acétyl-hydrolase du facteur d'activation plaquettaire appelés à réguler des manifestations inflammatoires pathologiques.

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