Truncated reelin protein and dna encoding the same

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) C07K 14/435 (2006.01) C07K 14/46 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2341786

The present invention provides a truncated Reelin protein containing a F-spondin domain and a CR-50 recognition site but containing no repeat site of a Reelin protein, and a DNA encoding the truncated Reelin protein. The truncated Reelin protein and the DNA encoding this protein of the present invention can be utilized for treatment of diseases including agyria due to abnormal alignment of neurons.

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