Trycyclic acetic acid derivatives

Details Trycyclic acetic acid derivatives Trycyclic acetic acid derivatives

C - Chemistry, Metallurgy

07

D

260/317

C07D 209/56 (2006.01)

Patent

CA 1046519

Tricyclic Acetic Acid Derivatives Abstract of the Disclosure Tetrahydrocyclopent[b]indole-3-acetic acid, tetrahydrocarbazole-1-acetic acid and hexahydrocyclohept[b]- indole-6-acetic acid derivatives in which the carbon bearing the acetic acid residue is further substituted with a lower alkyl, lower alkenyl or lower cycloalkyl are disclosed. The compounds are useful antiinflammatory agents and methods for their preparation and use are described. The compounds are represented by the following formula in which R1 is lower alkyl, lower alkenyl or lower cycloalkyl, R2 is hydrogen or lower alkyl, R3 is hydrogen, lower alkyl, halo, hydroxy, lower alkoxy, lower alkanoyloxy or trihalomethyl, R4 is hydrogen or lower alkyl and n is an integer from two to four. Image - 1 - _ I _

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