Tryparedoxin, expression plasmid, process of production,...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/53 (2006.01) C07K 14/44 (2006.01) C12N 5/10 (2006.01) C12N 9/02 (2006.01) C12N 9/08 (2006.01) C12Q 1/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2275175

The present invention describes novel enzymes, tryparedoxins, their isolation from Crithidia fasciculata, a method for the production thereof in genetically transformed bacteria, and their use as molecular targets for the discovery of trypanocidal drugs.

La présente invention concerne de nouvelles enzymes appelées tryparédoxines, leur isolement de Crithidia fasciculata, un procédé de production desdites enzymes dans des bactéries génétiquement modifiées, et leur utilisation comme cibles moléculaires pour la mise au point de trypanocides.

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