C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/36 (2006.01) C07C 279/20 (2006.01) C07C 279/36 (2006.01) C07C 311/64 (2006.01) C07D 209/32 (2006.01) C07D 209/36 (2006.01) C07D 277/34 (2006.01) C07D 311/08 (2006.01) C07D 311/16 (2006.01) C07D 333/32 (2006.01) C12Q 1/37 (2006.01)
Patent
CA 2334827
A compound of the formula (I) (see formula I) wherein R1 is a protecting group for N.alpha., R2 is a protecting group for NG, and R3 is aryl, and wherein the compound of formula (I) is a trypsin substrate such that trypsin cleaves the O-C single bond, which liberates R3-OH; a diagnostic device comprising same; a method for preparing the diagnostic device; and a method of using the diagnostic device to detect levels of urinary trypsin inhibitor in a biological sample; and a diagnostic kit for detecting levels of urinary trypsin inhibitor in a biological sample.
Corey Paul F.
Felman Steven W.
Pugia Michael J.
Rehm Gary E.
Corporation Bayer
Osler Hoskin & Harcourt Llp
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