Tryptamine analogues, their synthesis and their use as...

Details Tryptamine analogues, their synthesis and their use as... Tryptamine analogues, their synthesis and their use as...

C - Chemistry, Metallurgy

07

D

C07D 209/16 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2110574

2110574 9300333 PCTABS00019 Compounds of structure (I), in which R1 is hydrogen, hydroxy, C1-4alkoxy, halo C1-4alkoxy, C3-7cycloalkyl-C1-4alkoxy, aryloxy or arylC1-4alkoxy; R2 is halogen, C1-4alkyl, CN, NO2 or CF3; R3 is hydrogen or C1-4alkyl; R4 and R5 are the same or different and are each hydrogen or C1-4alkyl or together with the nitrogen atom to which they are attached form a ring; and their pharmaceutically acceptable salts, solvates and hydrates for use in conditions where a 5-HT1-like or 5-HT2 agonist is indicated. Novel compounds of structure (I), processes for preparing them and compositions containing them are also described.

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