Tsg101 as inhibitor of hiv production

Details Tsg101 as inhibitor of hiv production Tsg101 as inhibitor of hiv production

A - Human Necessities

61

K

A61K 39/21 (2006.01) A01N 43/04 (2006.01) C07K 14/16 (2006.01) C07K 14/47 (2006.01) C12N 5/00 (2006.01) C12N 15/00 (2006.01) C12N 15/63 (2006.01) C12N 15/64 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2448014

The present invention provides methods for identifying peptides in a mammalian Tsg101 protein that binds to the PTAPP motif or L domain of human immunodeficiency virus type I (HIV-1). Such peptides can be used to inhibit Tsg101-HIV Gag binding, and is therefore effective in reducing HIV particle production. The invention also provides the peptides identified by the method of the invention and to method of using such peptides for treating HIV infection.

L'invention concerne des procédés destinés à identifier des peptides dans une protéine Tsg101 qui se lie à un motif PTAPP ou à un domaine L du virus de l'immunodéficience humaine de type I (VIH-1). Ces peptides peuvent être utilisés afin d'inhiber la liaison Tsg101-Gag du VIH, et sont efficaces dans la réduction de la production de particules VIH. Cette invention concerne également les peptides identifiés par le procédé de l'invention et un procédé d'utilisation de ces peptides dans le traitement de l'infection par VIH.

Affiliated with

Also associated with

Rating

Tsg101 as inhibitor of hiv production does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tsg101 as inhibitor of hiv production, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tsg101 as inhibitor of hiv production will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1629619