Tuberculosis antigens and methods of use therefor

Details Tuberculosis antigens and methods of use therefor Tuberculosis antigens and methods of use therefor

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/04 (2006.01) A61P 31/06 (2006.01) C07K 14/35 (2006.01) C07K 16/12 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) A61K 35/12 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2364670

Compounds and methods for the diagnosis and treatment of tuberculosis are disclosed. Compounds include the M. tuberculosis antigens Mtb-81 and Mtb-67.2, immunogenic portions thereof and polynucleotides that encode such portions. Such compositions may be used, for example, for the immunotherapy and serodiagnosis ofM. tuberculosis infection.

L'invention concerne des composés et des procédés de diagnostic et de traitement de la tuberculose. Ces composés comprennent les antigènes de M. tuberculosis Mtb-81 et Mtb-67.2, leur parties immunogènes et les polynucléotides codant ces parties. Ces compositions peuvent, par exemple, s'utiliser dans l'immunothérapie et le sérodiagnostic de l'infection par M. tuberculosis.

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