Tubulin binding anti cancer agents and prodrugs thereof

A - Human Necessities – 61 – K

Patent

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A61K 31/4745 (2006.01)

Patent

CA 2587210

Novel tubulin binding compounds and hypoxia activated prodrugs of novel and known tubulin binding compounds useful for treating cancer and other hyperproliferative diseases are disclosed.

La présente invention a trait à de nouveaux composés de liaison à la tubuline et des prodrogues activés par l'hypoxie et des composés connus de liaison à la tubuline utiles pour le traitement du cancer et d'autres maladies hyperprolifératives.

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