Tumor-associated antigen, antibodies, compositions and uses...

C - Chemistry – Metallurgy – 12 – P

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167/139, 530/15,

C12P 21/08 (2006.01) A61K 39/395 (2006.01) A61K 39/44 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/30 (2006.01) C12N 5/18 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2016385

H-7327C ABSTRACT An antigen, characterized by its reactivity to monoclonal antibody CCK061 and antibody CCR086, is a glycoprotein having a molecular weight in the range of about 600,000 to about 1,000,000 daltons and isoelectric points in the ranges of about 4.3 to about 4.5 and about 4.8 to about 5Ø Antibodies directed against the antigen, methods for their production and diagnostic and therapeutic uses therefor are provided.

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