C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) C07K 14/47 (2006.01)
Patent
CA 2568254
The invention relates to a tumor-associated peptide with an amino acid sequence that is selected from the group consisting of SEQ ID-Nr. 1 to SEQ ID- Nr. 577 from the annexed sequence protocol. The peptide is capable of binding to a molecule of the human main histocompatibility complex (MHC) class I. The invention also relates to the use of peptides for producing a medicament and for treating tumor diseases and/or adenomatous diseases. The invention also relates to a pharmaceutical composition containing at least one of the peptides.
L'invention concerne un peptide spécifique de tumeurs, qui présente une séquence d'aminoacide, sélectionnée dans le groupe comprenant SEQ ID n°1 à SEQ ID N°577, du protocole de séquences joint, ledit peptide étant apte à se fixer sur une molécule de la catégorie I du complexe majeur d'histocompatibilité principal humain (CMH). L'invention concerne en outre l'utilisation des peptides pour produire un médicament et pour traiter des maladies tumorales et/ou des pathologies adénomateuses. L'invention concerne par ailleurs une composition pharmaceutique qui présente au moins un desdits peptides.
Lemmel Claudia
Rammensee Hans-Goerg
Stevanovic Stefan
Weinschenk Toni
Heenan Blaikie Llp
Immatics Biotechnologies Gmbh
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