Tumor cell differentiation agents as chemical inhibitors and...

A - Human Necessities – 61 – K

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A61K 31/167 (2006.01) A61K 31/166 (2006.01) A61P 33/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2647359

The present invention provides new compositions and methods for treatment of intracellular parasites. The compositions comprise one or more hydroxamic acids in an amount sufficient to interfere with the activity of one or more histone deacetylases in the intracellular parasites. The compositions and methods can be used to treat members of the Apicomplexa group of intracellular parasites.

La présente invention concerne de nouvelles compositions et de nouveaux procédés destinés au traitement de parasites intracellulaires. Les compositions contiennent un ou plusieurs acides hydroxamiques dans une quantité suffisante pour affecter l'activité d'une ou de plusieurs histones désacétylases dans les parasites intracellulaires. Les compositions et procédés peuvent être utilisés pour traiter des membres du groupe Apicomplexa de parasites intracellulaires.

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