Tumor endothelial marker 7.alpha. molecules and uses thereof

Details Tumor endothelial marker 7.alpha. molecules and uses thereof Tumor endothelial marker 7.alpha. molecules and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2447916

The present invention provides Tumor Endothelial Marker 7.alpha. (TEM7.alpha.) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing TEM7.alpha. polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with TEM7.alpha. polypeptides.

L'invention concerne des polypeptides de marqueur endothélial tumoral 7.alpha. (TEM7.alpha.) et des molécules d'acide nucléique codant ceux-ci. L'invention concerne également des agents de liaison sélectifs, des vecteurs sélectifs, des cellules hôtes sélectives et de procédés sélectifs de préparation des polypeptides de TEM7.alpha.. L'invention concerne enfin des compositions pharmaceutiques et des méthodes de diagnostic, de traitement, d'amélioration et/ou de prévention de maladies, de troubles et d'états associés aux polypeptides de TEM7.alpha..

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