Tumor imaging with radiolabeled monoclonal antibodies

Details Tumor imaging with radiolabeled monoclonal antibodies Tumor imaging with radiolabeled monoclonal antibodies

G - Physics

01

N

167/47, 195/1.1

G01N 33/577 (2006.01) A61K 39/395 (2006.01) A61K 51/10 (2006.01)

Patent

CA 1202892

ABSTRACT Described herein are monoclonal antibodies to tumor associated antigens to which are bound a metallic radionuclide, either directly or by means of a chelating agent such as di- ethylenetriaminepentaacetic acid (DTPA) conjugated to the antibody. When parenterally administered to a subject, the labeled monoclonal antibody localizes in the tumor and can be detected by photoscanning to detect emitted radiation.

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